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Red blood cells: a potential delivery system

Mengran Chen, Yamei Leng, Chuan He, Xuefeng Li, Lei Zhao, Ying Qu, Yu Wu

2023Journal of Nanobiotechnology53 citationsDOIOpen Access PDF

Abstract

Red blood cells (RBCs) are the most abundant cells in the body, possessing unique biological and physical properties. RBCs have demonstrated outstanding potential as delivery vehicles due to their low immunogenicity, long-circulating cycle, and immune characteristics, exhibiting delivery abilities. There have been several developments in understanding the delivery system of RBCs and their derivatives, and they have been applied in various aspects of biomedicine. This article compared the various physiological and physical characteristics of RBCs, analyzed their potential advantages in delivery systems, and summarized their existing practices in biomedicine.

Topics & Concepts

BiomedicineImmunogenicityDelivery systemImmune systemNanotechnologyChemistryBiologyBiomedical engineeringMedicineBioinformaticsImmunologyMaterials scienceErythrocyte Function and PathophysiologyBlood properties and coagulationHemoglobin structure and function
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