Investigation of the effects of two major secretory granules components, insulin and zinc, on human-IAPP amyloid aggregation and membrane damage
Lucie Khemtémourian, Federico Antoniciello, Bikash R. Sahoo, Marion Décossas, Sophie Lecomte, Ayyalusamy Ramamoorthy
Topics & Concepts
ChemistryAmylinBiophysicsAmyloid (mycology)FibrilIsletMembraneHistidineResidue (chemistry)ZincBiochemistryCircular dichroismPeptideInsulinThioflavinPancreatic isletsExtracellularAmino acidInternal medicineAlzheimer's diseaseMedicineInorganic chemistryBiologyDiseaseOrganic chemistryPancreatic function and diabetesAlzheimer's disease research and treatmentsEndoplasmic Reticulum Stress and Disease