Risk profiling and efficacy of albendazole against the hookworms Necator americanus and Ancylostoma ceylanicum in Cambodia to support control programs in Southeast Asia and the Western Pacific
Vito Colella, Virak Khieu, Andrew Worsley, Dammika Senevirathna, Sinuon Muth, Rekol Huy, Peter Odermatt, Rebecca J. Traub
Abstract
Background: Hookworm disease is endemic throughout many parts of the Asia Pacific, despite targeted control programs of at-risk populations. The success of these programs has been hindered by the limited efficacy of widely-used mebendazole, rapid re-infection rates linked to persistent reservoirs of untreated people and dogs, and the low sensitivity of conventional coprodiagnostic techniques employed.
Topics & Concepts
Necator americanusAlbendazoleHookworm infectionHookworm InfectionsMebendazoleAncylostomaOdds ratioBiologyAnthelminticMass drug administrationEnvironmental healthMedicineVeterinary medicineHelminthiasisImmunologyHelminthsInternal medicinePopulationAscaris lumbricoidesSurgeryEcologyParasites and Host InteractionsParasite Biology and Host InteractionsHelminth infection and control