Multifunctional Antibiotic–Host Defense Peptide Conjugate Kills Bacteria, Eradicates Biofilms, and Modulates the Innate Immune Response
Hashem Etayash, Morgan A. Alford, Noushin Akhoundsadegh, Matthew Drayton, Suzana K. Straus, Robert E. W. Hancock
Abstract
efficacy of the conjugate, in addition to its safety profile, makes it a valuable candidate to treat complex infectious diseases.
Topics & Concepts
Innate immune systemMicrobiologyAntibioticsChemistryImmune systemBiofilmBacteriaPeptideHost (biology)ConjugateImmunologyBiologyBiochemistryGeneticsMathematicsEcologyMathematical analysisAntimicrobial Peptides and ActivitiesBacterial biofilms and quorum sensingOral microbiology and periodontitis research