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Single-cell analysis reveals immune dysfunction from the earliest stages of CLL that can be reversed by ibrutinib

Purroy, Noelia, Tong, Yuzhou Evelyn, Lemvigh, Camilla K., Cieri, Nicoletta, Li, Shuqiang, Parry, Erin M., Zhang, Wandi, Rassenti, Laura Z., Kipps, Thomas J., Slager, Susan L., Kay, Neil E., Lesnick, Connie, Shanafelt, Tait D., Ghia, Paolo, Scarfò, Lydia, Livak, Kenneth J., Kharchenko, Peter V., Neuberg, Donna S., Olsen, Lars Rønn, Fan, Jean, Gohil, Satyen H., Wu, Catherine J.

2022Technical University of Denmark, DTU Orbit (Technical University of Denmark, DTU)16 citations

Topics & Concepts

IbrutinibImmune systemMedicineBruton's tyrosine kinaseImmunologyCancer researchInternal medicineLeukemiaChronic lymphocytic leukemiaReceptorTyrosine kinaseChronic Lymphocytic Leukemia ResearchLymphoma Diagnosis and TreatmentImmunodeficiency and Autoimmune Disorders
Single-cell analysis reveals immune dysfunction from the earliest stages of CLL that can be reversed by ibrutinib | Litcius