Dissipation and risk assessment of forchlorfenuron and its major metabolites in oriental melon under greenhouse cultivation
Qi Wang, Hang Su, Ning Yue, Minjie Li, Chunmei Li, Jing Wang, Fen Jin
Abstract
Forchlorfenuron is a widely used plant growth regulator. The uptake of forchlorfenuron and its major metabolites poses a potential risk for human health. However, little is known about the dissipation of forchlorfenuron and its major metabolites in agricultural food. In this study, the metabolite 4-hydroxyphenyl-forchlorfenuron was first identified in oriental melon, which exhibited the highest level of residues of 4.42-5.12 μg/kg on the 4-7th days after application. Forchlorfenuron was found to be dissipated rapidly in melon at the recommended application rates, with half-lives ranging from 1.20 to 1.33 days. The rate of dissipation of 4-hydroxyphenyl-forchlorfenuron was greater than that of metabolism from forchlorfenuron in the oriental melon. However, the other metabolite, 3-hydroxyphenyl-forchlorfenuron, was not detected in oriental melon. The risk assessment showed that the acute and chronic dietary exposure risks of forchlorfenuron in oriental melon were 0.0011-0.0037% and 0.06-0.12%, respectively, suggesting little health risk to Chinese consumers.