Multi-omic profiling of plasma reveals molecular alterations in children with COVID-19
Chong Wang, Xufang Li, Wanshan Ning, Sitang Gong, Fengxia Yang, Chunxiao Fang, Yu Gong, Di Wu, Muhan Huang, Yujie Gou, Shanshan Fu, Yujie Ren, Ruyi Yang, Yang Qiu, Yu Xue, Yi Xu, Xi Zhou
Abstract
The finding of a strong antagonism of deteriorative and protective effects provided new insights on the mechanism and pathogenesis of COVID-19 in children that mostly underwent mild symptoms. The identified metabolites strongly altered in COVID-19-children could serve as potential therapeutic agents of COVID-19.
Topics & Concepts
Coronavirus disease 2019 (COVID-19)CoronavirusMetabolomicsMedicineInflammationOmicsSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Immune systemMetabolomeBioinformaticsImmunologyDiseaseBiologyInfectious disease (medical specialty)Internal medicineCOVID-19 Clinical Research StudiesLong-Term Effects of COVID-19SARS-CoV-2 and COVID-19 Research