A near-infrared fluorescent nanoprobe for senescence-associated β-galactosidase sensing in living cells
Ye Zhao, Shan Sun, Yan Lyu, Mengyao Gao, Hengwei Lin, Cheng Yang
Abstract
A near-infrared fluorescent nanoprobe based on semiconducting polymer nanoparticles (SPNs) for the detection of senescence-associated β-gal (SA-β-gal) is developed. Benefiting from the intrinsic lysosome-locating feature, this probe can be successfully used for the visualization of SA-β-gal in living cells.
Topics & Concepts
NanoprobeFluorescenceInfraredLysosomeBiophysicsChemistryNanotechnologyCell biologyNanoparticleMaterials scienceBiochemistryBiologyEnzymeOpticsPhysicsAdvanced biosensing and bioanalysis techniquesElectrochemical sensors and biosensorsAdvanced Nanomaterials in Catalysis