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Free-Radical-Promoted Dehydrogenative Coupling of Polyfluorinated Alcohol with Quinone, Chromone, and Coumarin

Jingping Liu, Dan Yu, Yong Sheng Yang, Huichao You, Minzhi Sun, Yaxin Wang, Xu Shen, Zhong‐Quan Liu

2020Organic Letters44 citationsDOI

Abstract

A free-radical-mediated dehydrogenative cross-coupling reaction of polyfluorinated alcohol with quinone, coumarin, and chromone was developed. It provides a sustainable and practical strategy for installation of fluorine atom into organic molecules by using polyfluorinated alcohols.

Topics & Concepts

ChromoneChemistryCoumarinAlcoholQuinoneFluorinePhotochemistryCombinatorial chemistryCoupling (piping)Organic chemistryMechanical engineeringEngineeringCatalytic C–H Functionalization MethodsRadical Photochemical ReactionsOxidative Organic Chemistry Reactions
Free-Radical-Promoted Dehydrogenative Coupling of Polyfluorinated Alcohol with Quinone, Chromone, and Coumarin | Litcius