Insulin receptor substrate in brain-enriched exosomes in subjects with major depression: on the path of creation of biosignatures of central insulin resistance
Carla Nasca, Josh Dobbin, Benedetta Bigio, Kathleen Watson, Paolo De Angelis, Marin Kautz, Ashly Cochran, Aleksander A. Mathé, James H. Kocsis, Francis S. Lee, James W. Murrough, Bruce S. McEwen, Natalie Rasgon
Topics & Concepts
Insulin resistanceInsulin receptorMajor depressive disorderAnhedoniaInsulin receptor substrateInternal medicineInsulinEndocrinologyMicrovesiclesNeuroplasticityNeuroscienceMedicinePsychologyBiologymicroRNAGeneBiochemistryAmygdalaDopamineExtracellular vesicles in diseaseRegulation of Appetite and ObesityNeuroinflammation and Neurodegeneration Mechanisms