Primary Macrophage-Based Microrobots: An Effective Tumor Therapy <i>In Vivo</i> by Dual-Targeting Function and Near-Infrared-Triggered Drug Release
Van Du Nguyen, Hyun-Ki Min, Ho Yong Kim, Jiwon Han, You Hee Choi, Chang‐Sei Kim, Jong-Oh Park, Eunpyo Choi
Abstract
experiments confirmed that the application of the magnetic field and NIR laser could markedly inhibit the growth of tumors with a subtherapeutic dose of DOX and a single injection of the microrobots. In summary, the study proposes a strategy for the effective anticancer treatment using the developed microrobots.
Topics & Concepts
In vivoPhotothermal therapyDrug deliveryImmune systemDoxorubicinCancer researchMacrophageTargeted drug deliveryIn vitroMaterials scienceBiomedical engineeringNanotechnologyBiophysicsChemistryImmunologyMedicineChemotherapyBiologyBiochemistryBiotechnologySurgeryMicro and Nano RoboticsNanoplatforms for cancer theranosticsNanoparticle-Based Drug Delivery