Genetic and Epigenetic Etiology of Inflammatory Bowel Disease: An Update
Sara Jarmakiewicz-Czaja, Magdalena Zielińska, Aneta Sokal, Rafał Filip
Abstract
Inflammatory bowel disease (IBD) is a chronic disease with periods of exacerbation and remission of the disease. The etiology of IBD is not fully understood. Many studies point to the presence of genetic, immunological, environmental, and microbiological factors and the interactions between them in the occurrence of IBD. The review looks at genetic factors in the context of both IBD predisposition and pharmacogenetics.
Topics & Concepts
Inflammatory bowel diseaseEtiologyContext (archaeology)Genetic predispositionDiseaseExacerbationMedicineUlcerative colitisPharmacogeneticsImmunologyGeneticsBiologyPathologyGeneGenotypePaleontologyInflammatory Bowel DiseaseHelicobacter pylori-related gastroenterology studiesTuberculosis Research and Epidemiology