Efficient and eco-friendly oxidative cleavage of C–C bonds of 1,2-diols to ketones: electrochemistry <i>vs</i> thermochemistry
Rui Wang, Pengchao Sun, Weiwei Jin, Yonghong Zhang, Bin Wang, Yu Xia, Fei Xue, Ablimit Abdukader, Chenjiang Liu
Abstract
Two protocols are established to the synthesis of ketones by the oxidative cleavage C-C bonds of vicinal diols under electrochemical and thermochemical strategies. The substrate scopes and preliminary mechanisms of these two protocols are discussed.
Topics & Concepts
ChemistryThermochemistryVicinalOxidative cleavageElectrochemistryBond cleavageCleavage (geology)Oxidative phosphorylationCombinatorial chemistrySubstrate (aquarium)StereochemistryMedicinal chemistryOrganic chemistryCatalysisInorganic chemistryElectrodePhysical chemistryFracture (geology)EngineeringBiochemistryGeotechnical engineeringGeologyOceanographyOxidative Organic Chemistry ReactionsChemical Synthesis and ReactionsRadical Photochemical Reactions