Heparin Resistance — Clinical Perspectives and Management Strategies
Jerrold H. Levy, Jean M. Connors
Abstract
Heparin resistance is suspected when more heparin than usual is needed to achieve a therapeutic range of activated partial-thromboplastin time. Management may include increasing the heparin dose, supplementing antithrombin III levels, and using direct thrombin inhibitors.
Topics & Concepts
HeparinPartial thromboplastin timeThrombinAntithrombinMedicineThrombin timeAnticoagulantPharmacologyIntensive care medicineInternal medicineCoagulationPlateletHeparin-Induced Thrombocytopenia and ThrombosisVenous Thromboembolism Diagnosis and ManagementCase Reports on Hematomas