Sustainable production of rare oleanane-type ginsenoside Ro with an artificial glycosylation pathway in <i>Saccharomyces cerevisiae</i>
Shi‐Chao Ren, Qiuyan Sun, Liang Zhang, Wentao Sun, Yongxing Li, Xudong Feng, Chun Li
Abstract
S. cerevisiae was genetically reprogrammed to produce ginsenoside Ro with seven exogenous enzymes from five species. This study also paved a good way for the synthesis of other complex glycosides of triterpenoids.
Topics & Concepts
Saccharomyces cerevisiaeOleananeGlycosylationChemistryGlycosideBiochemistryGinsenosideTriterpenoidEnzymeYeastTriterpeneStereochemistryMedicineGinsengAlternative medicinePathologyNatural product bioactivities and synthesisGinseng Biological Effects and ApplicationsPlant biochemistry and biosynthesis