Halide-free and metal-free allylic thiolation/selenation of P(O)H compounds with sulfur/selenium and allylic alcohols
Longzhi Zhu, Weiwei Luo, Furong Guo, Lin Chen, Ying Tang, Biquan Xiong, Yu Liu, Kewen Tang, Renhua Qiu
Abstract
A halide- and metal-free method for forming C–S/Se–P(O) bonds using allylic alcohols, P(O)H compounds, and elemental sulfur/selenium is reported, eliminating the need for toxic, odorous, and moisture-sensitive starting materials.
Topics & Concepts
Allylic rearrangementSeleniumHalideSulfurChemistryMetalOrganic chemistryMedicinal chemistryInorganic chemistryCatalysisSulfur-Based Synthesis TechniquesChemical Synthesis and ReactionsCatalytic C–H Functionalization Methods