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Morpholine Derivatives in Agrochemical Discovery and Development

Xu Tang, Li Lei, Anjing Liao, Wei Sun, Jian Zhang, Jian Wu

2023Journal of Agricultural and Food Chemistry17 citationsDOI

Abstract

Derivatives of morpholine are biologically active organic compounds with special structures discovered in multiple drugs. As a result of the terminal pharmacophore of action and extraordinary activity, they attracted fair attention with regard to pesticide innovation and development. Analysis of brief structure-activity relationships and the summarization of the characteristics of pesticides containing morpholine fragments with efficient activity are key steps in the development of novel pesticides. This review primarily overviews morpholine compounds with insecticidal, fungicidal, herbicidal, antiviral, and plant growth regulation properties to provide educational insight for the creation of new morpholine-containing compounds.

Topics & Concepts

MorpholineAgrochemicalChemistryDrug discoveryEnvironmental chemistryOrganic chemistryBiologyBiochemistryAgricultureEcologySynthesis and Biological EvaluationN-Heterocyclic Carbenes in Organic and Inorganic Chemistry
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