Design, synthesis, and biological evaluation of novel benzimidazolyl isoxazole derivatives as potential c-Myc G4 stabilizers to suppress c-Myc transcription and myeloma growth
Xiaoju Geng, Yan Zhang, Shi-Hao Li, Linlin Liu, Ruosi Yao, Ling Liu, Jian Gao
Topics & Concepts
ChemistryIsoxazoleOncogeneIn vitroGeneTranscription (linguistics)Small moleculeCancer researchStereochemistryMolecular biologyBiochemistryCell cycleBiologyLinguisticsPhilosophyDNA and Nucleic Acid ChemistryAdvanced biosensing and bioanalysis techniquesRNA Interference and Gene Delivery