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Structures of α-synuclein filaments from multiple system atrophy

Manuel Schweighauser, Yang Shi, Airi Tarutani, Fuyuki Kametani, Alexey G. Murzin, Bernardino Ghetti, Tomoyasu Matsubara, Taisuke Tomita, Takashi Ando, Kazuko Hasegawa, Shigeo Murayama, Mari Yoshida, Masato Hasegawa, Sjors H. W. Scheres, Michel Goedert

2020Nature833 citationsDOIOpen Access PDF

Topics & Concepts

SynucleinopathiesDementia with Lewy bodiesAtrophyNeurodegenerationHuman brainAlpha-synucleinNeuroscienceBiologyAmyloid (mycology)Lewy bodyDementiaParkinson's diseasePathologyMedicineDiseaseParkinson's Disease Mechanisms and TreatmentsNeurological diseases and metabolismBotulinum Toxin and Related Neurological Disorders
Structures of α-synuclein filaments from multiple system atrophy | Litcius