Treatment of severe Kaposiform lymphangiomatosis positive for NRAS mutation by MEK inhibition
Guy Chowers, Gadi Abebe‐Campino, Hana Golan, Asaf Vivante, Shoshana Greenberger, Michalle Soudack, Galia Barkai, Ilana Fox-Fisher, Dong Li, Michael March, Mark R. Battig, Håkon Håkonarson, Denise M. Adams, Yoav Dori, Adi Dagan
Topics & Concepts
TrametinibNeuroblastoma RAS viral oncogene homologLymphangiomatosisCancer researchMAPK/ERK pathwayLymphatic systemMEK inhibitorPI3K/AKT/mTOR pathwayMedicineMutationBiologyImmunologyKRASCell biologySignal transductionGeneticsGeneVascular Malformations and HemangiomasCNS Lymphoma Diagnosis and TreatmentViral-associated cancers and disorders