Covalently functionalized poly(etheretherketone) implants with osteogenic growth peptide (OGP) to improve osteogenesis activity
Maihemuti Yakufu, Zongliang Wang, Yu Wang, Zixue Jiao, Min Guo, Jianguo Liu, Peibiao Zhang
Abstract
results reveal that the modification by covalent chemical functionalization with OGP on PEEK surface can augment new bone formation surrounding implants compared to bare PEEK and PEEK implant modified by covalently attached OGP is promising in orthopedic and dental applications.
Topics & Concepts
PeekSurface modificationOsseointegrationCovalent bondMaterials scienceX-ray photoelectron spectroscopyAlkaline phosphataseFourier transform infrared spectroscopyOsteoblastChemistryDental implantPolymer chemistryChemical engineeringImplantIn vitroPolymerComposite materialOrganic chemistryBiochemistrySurgeryPhysical chemistryEngineeringEnzymeMedicineBone Tissue Engineering Materialsbiodegradable polymer synthesis and propertiesOrthopaedic implants and arthroplasty