Combined exposure to non-antibiotic pharmaceutics and antibiotics in the gut synergistically promote the development of multi-drug-resistance in <i>Escherichia coli</i>
Danyang Shi, Han Hao, Zilin Wei, Dong Yang, Jing Yin, Haibei Li, Zhengshan Chen, Zhongwei Yang, Tianjiao Chen, Shuqing Zhou, Haiyan Wu, Jùnwén Lǐ, Min Jin
Abstract
. Our findings demonstrated that antibiotics and non-antibiotic pharmaceutics synergistically accelerate the evolution of ARB and may enhance their spread.
Topics & Concepts
ChloramphenicolAntibioticsMicrobiologyBiologyEscherichia coliAntibiotic resistanceTetracyclineEffluxGeneBiochemistryGut microbiota and healthClostridium difficile and Clostridium perfringens researchPharmaceutical and Antibiotic Environmental Impacts