Visible-light-mediated direct C3 alkylation of quinoxalin-2(1<i>H</i>)-ones using alkanes
Kaikai Niu, Jing Cui, Rui-Zhi Dong, Shengsheng Yu, Hui Liu, Ling‐Bao Xing
Abstract
)-ones using trifluoroacetic acid as a hydrogen atom transfer reagent and air as an oxidant. This mild protocol was performed under metal- and photocatalyst-free circumstances and presented good functional-group tolerance as well as a broad substrate scope.
Topics & Concepts
AlkylationChemistryMedicinal chemistryVisible spectrumOrganic chemistryCatalysisMaterials scienceOptoelectronicsRadical Photochemical ReactionsCatalytic C–H Functionalization MethodsSynthesis and Biological Evaluation