Toll like receptor-based electrochemical sensors <i>via</i> N-heterocyclic carbene-modified surfaces: towards improved sensing of DNA molecules
Dianne Lee, Mir Pouyan Zarabadi, Hridaynath Bhattacharjee, Qi Lin, Jennifer F. McLeod, Kasra Saeedfar, Ishwar Singh, April Woods, Anastasia Messina, Viola Birss, Cathleen M. Crudden, Zhe She
Abstract
New method for synthesizing novel N-heterocyclic carbenes and using them for protein biosensors detecting DNA molecules.
Topics & Concepts
DNABiosensorMoleculeCombinatorial chemistryChemistryElectrochemistryCarbeneAptamerToll-like receptorSmall moleculeReceptorNanotechnologyMaterials scienceBiochemistryElectrodeMolecular biologyBiologyOrganic chemistryCatalysisPhysical chemistryInnate immune systemMolecular Junctions and NanostructuresAdvanced biosensing and bioanalysis techniquesDNA and Nucleic Acid Chemistry