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The YAP–TEAD complex promotes senescent cell survival by lowering endoplasmic reticulum stress

Carlos Anerillas, Krystyna Mazan-Mamczarz, Allison B. Herman, Rachel Munk, Kwan-Wood Gabriel Lam, Miguel Calvo‐Rubio, Amanda Garrido, Dimitrios Tsitsipatis, Jennifer L. Martindale, Gisela Altés, Martina Rossi, Yulan Piao, Jinshui Fan, Chang‐Yi Cui, Supriyo De, Kotb Abdelmohsen, Rafael de Cabo, Myriam Gorospe

2023Nature Aging69 citationsDOIOpen Access PDF

Topics & Concepts

Endoplasmic reticulumCell biologyUnfolded protein responseProgrammed cell deathBiologySenescenceApoptosisPI3K/AKT/mTOR pathwaySignal transductionCancer researchBiochemistryHippo pathway signaling and YAP/TAZAutophagy in Disease and TherapyCRISPR and Genetic Engineering
The YAP–TEAD complex promotes senescent cell survival by lowering endoplasmic reticulum stress | Litcius