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A Combined Halogen‐ and Chalcogen‐Bonding Organocatalyst

Dhananjoy Pal, T. Steinke, Lukas Vogel, Elric Engelage, Sascha Heinrich, Dana Kutzinski, Stefan M. Huber

2023Advanced Synthesis & Catalysis28 citationsDOIOpen Access PDF

Abstract

Abstract Applications of both halogen and chalcogen bonding in organocatalysis are by now well established with various examples. However, the combination of both interactions within one catalyst is currently unknown. Herein, we describe the synthesis of such a mixed chalcogen‐ and halogen‐bond donor and present a first indication of its catalytic activity in a benchmark reaction.

Topics & Concepts

ChalcogenChemistryOrganocatalysisHalogen bondHalogenCatalysisCombinatorial chemistryBenchmark (surveying)Organic chemistryEnantioselective synthesisGeodesyGeographyAlkylCrystallography and molecular interactionsAsymmetric Synthesis and CatalysisOrganic Chemistry Cycloaddition Reactions
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