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Molecular dynamic simulation suggests stronger interaction of Omicron-spike with ACE2 than wild but weaker than Delta SARS-CoV-2 can be blocked by engineered S1-RBD fraction

Dipannita Santra, Smarajit Maiti

2022Structural Chemistry26 citationsDOIOpen Access PDF

Topics & Concepts

ChemistryDocking (animal)Protein Data Bank (RCSB PDB)Molecular dynamicsWild typeMutantCrystallographyStereochemistryRamachandran plotBiophysicsProtein structureBiochemistryComputational chemistryBiologyNursingGeneMedicineSARS-CoV-2 and COVID-19 Researchvaccines and immunoinformatics approachesComputational Drug Discovery Methods
Molecular dynamic simulation suggests stronger interaction of Omicron-spike with ACE2 than wild but weaker than Delta SARS-CoV-2 can be blocked by engineered S1-RBD fraction | Litcius