Litcius/Paper detail

Recent developments in the synthesis of azaindoles from pyridine and pyrrole building blocks

Damoder Reddy Motati, Radhika Amaradhi, Thota Ganesh

2020Organic Chemistry Frontiers46 citationsDOI

Abstract

The azaindole framework is ubiquitous in bioactive natural products and pharmaceuticals. This review highlights the synthetic approaches to azaindoles with advantages and limitations, mechanistic pathways and biological importance.

Topics & Concepts

ChemistryPyridineCombinatorial chemistryPyrroleBiochemical engineeringNanotechnologyComputational biologyOrganic chemistryEngineeringBiologyMaterials scienceCatalytic C–H Functionalization MethodsSynthesis and Characterization of PyrrolesSynthesis of heterocyclic compounds