A versatile CRISPR Cas12a-based point-of-care biosensor enabling convenient glucometer readout for ultrasensitive detection of pathogen nucleic acids
Biyun Fang, Zhenzhen Jia, Cui Liu, Kangsheng Tu, Mingzhen Zhang, Lei Zhang
Topics & Concepts
Nucleic acidChemistryCRISPRPathogenDNARolling circle replicationLoop-mediated isothermal amplificationOligonucleotideNucleic acid quantitationMolecular biologyPolymeraseBiochemistryBiologyMicrobiologyGeneCRISPR and Genetic EngineeringAdvanced biosensing and bioanalysis techniquesBiosensors and Analytical Detection