Synthesis, characterization, and <i>in vivo</i> evaluation of the anticancer activity of a series of 5- and 6-(halomethyl)-2,2′-bipyridine rhenium tricarbonyl complexes
Sara Nasiri Sovari, Isabelle Kolly, Kevin Schindler, Ana Djurić, Tatjana Srdić‐Rajić, Aurélien Crochet, Aleksandar Pavić, Fabio Zobi
Abstract
The presence and position of a reactive halomethyl substituent on the diimine ligand system of fac -[Re(CO) 3 ] + complexes influences the anticancer activity of the compounds in zebrafish xenografts.
Topics & Concepts
RheniumCharacterization (materials science)In vivoSeries (stratigraphy)ChemistryBipyridineCombinatorial chemistryStereochemistryNanotechnologyOrganic chemistryMaterials scienceBiologyCrystal structurePaleontologyBiotechnologyMetal complexes synthesis and propertiesClick Chemistry and ApplicationsSynthesis of Tetrazole Derivatives