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New Insights Into Plaque Erosion as a Mechanism of Acute Coronary Syndromes

Dhaval Kolte, Peter Libby, Ik‐Kyung Jang

2021JAMA44 citationsDOI

Abstract

This Viewpoint summarizes the pathophysiology and clinical features of atherosclerotic plaque erosion as an underlying mechanism of acute coronary syndromes (ACS) distinct from plaque rupture and reviews evidence that antithrombotic therapy without PCI and stenting may be optimal treatment.

Topics & Concepts

MedicineAntithromboticAcute coronary syndromeMechanism (biology)PathophysiologyCardiologyConventional PCICoronary stentingIntensive care medicineInternal medicineStentMyocardial infarctionRestenosisEpistemologyPhilosophyCoronary Interventions and DiagnosticsCardiac Imaging and DiagnosticsCerebrovascular and Carotid Artery Diseases
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