Metal-free reductive acyldifluoroalkylation of alkenes through cooperative NHC and organophotocatalysis
Zhenhui Wang, Xiaofeng Li, Wei Li, Yongyong Cao, Huaifeng Li
Abstract
We introduce a reductive acyldifluoroalkylation method to synthesize β-difluoroalkyl ketones, which proceeds in a metal-free manner at room temperature.
Topics & Concepts
ChemistryMetalReductive eliminationPolymer chemistryCombinatorial chemistryOrganic chemistryCatalysisFluorine in Organic ChemistryN-Heterocyclic Carbenes in Organic and Inorganic ChemistryCyclopropane Reaction Mechanisms