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Imatinib-induced hepatotoxicity via oxidative stress and activation of NLRP3 inflammasome: an in vitro and in vivo study

Feng‐Ru Huang, Wentong Fang, Ziping Cheng, Ye Shen, Dun‐Jian Wang, Yongqing Wang, Luning Sun

2022Archives of Toxicology15 citationsDOI

Topics & Concepts

InflammasomeOxidative stressPharmacologyLiver injuryViability assayHepatoprotectionChemistryIn vivoMedicineApoptosisReceptorBiochemistryBiologyGlutathioneEnzymeBiotechnologyDrug-Induced Hepatotoxicity and ProtectionMyeloproliferative Neoplasms: Diagnosis and TreatmentChronic Myeloid Leukemia Treatments
Imatinib-induced hepatotoxicity via oxidative stress and activation of NLRP3 inflammasome: an in vitro and in vivo study | Litcius