Design, synthesis and evaluation of novel 9-arylalkyl-10-methylacridinium derivatives as highly potent FtsZ-targeting antibacterial agents
Di Song, Nan Zhang, Panpan Zhang, Na Zhang, Weijin Chen, Long Zhang, Ting Guo, Xiaotong Gu, Shutao Ma
Topics & Concepts
FtsZChemistryLinezolidCiprofloxacinAntibioticsEffluxAntibacterial activityMultiple drug resistanceCytotoxicityMicrobiologyPharmacologyBacteriaVancomycinStaphylococcus aureusIn vitroBiochemistryCell divisionCellBiologyGeneticsAntibiotic Resistance in BacteriaAntimicrobial Peptides and ActivitiesBacteriophages and microbial interactions