Lipid oxidation controls peptide self-assembly near membranes through a surface attraction mechanism
Torsten John, Stefania Piantavigna, Tiara J. A. Dealey, Bernd Abel, Herre Jelger Risselada, Lisandra L. Martin
Abstract
Oxidized model membranes have differential effects on peptide fibril formation, driven by surface attraction, peptide charge and secondary structure stabilization.
Topics & Concepts
PeptideMembranePOPCChemistryBiophysicsLipid bilayerMembrane lipidsP3 peptideBiochemistryAmyloid precursor proteinBiologyAlzheimer's diseaseDiseasePathologyMedicineLipid Membrane Structure and BehaviorAntimicrobial Peptides and ActivitiesSupramolecular Self-Assembly in Materials