A PDA-DTC/Cu–MnO<sub>2</sub> nanoplatform for MR imaging and multi-therapy for triple-negative breast cancer treatment
Xiaochun Hu, Yonglin Lu, Wenrong Zhao, Menglin Sun, Ruihao Li, Lei Feng, Tianming Yao, Chunyan Dong, Shuo Shi
Abstract
Herein, a multi-functional nanoplatform (PDA-DTC/Cu-MnO2) was established, which has been employed for MR imaging-guided multi-therapy (CDT, PTT and chemotherapy) for cancer treatment. The in vitro and in vivo results confirmed that the biocompatible nanoplatform could significantly induce tumor cell death and inhibit tumor growth.
Topics & Concepts
Triple-negative breast cancerBreast cancerMedicineCancer researchCancerOncologyInternal medicineNanoplatforms for cancer theranosticsNanoparticle-Based Drug DeliveryLanthanide and Transition Metal Complexes