Exploration of certain 1,3-oxazole- and 1,3-thiazole-based hydroxamic acids as histone deacetylase inhibitors and antitumor agents
Duong Tien Anh, Hai Pham‐The, Huong Le‐Thi‐Thu, Eun Jae Park, Hye Won Jun, Jong Soon Kang, Joo‐Hee Kwon, Đỗ Thị Mai Dung, Tran Anh Vu, Văn Thị Mỹ Huệ, Sang‐Bae Han, Nguyen‐Hai Nam
Topics & Concepts
ChemistryOxazoleThiazoleHistone deacetylaseIC50Hydroxamic acidVorinostatStereochemistryDocking (animal)CytotoxicityCombinatorial chemistryBiochemistryIn vitroHistoneNursingGeneMedicineHistone Deacetylase Inhibitors ResearchClick Chemistry and ApplicationsCholinesterase and Neurodegenerative Diseases