Metal-free radical bicyclization/chloroalkylarylation of 1,6-enynes with chloroalkanes
Hongxun Zhou, Lijun Li, Qinqin Yan, Jinyue Ma, Ying Wang, Gao Y, Zhong‐Quan Liu, Zejiang Li
Abstract
)-H bond of the chloralkane, resulting in diverse polychlorinated/chlorinated polyheterocycles. Two kinds of transformations and a scaled-up experiment were performed to test the synthetic importance of the organic chlorides. Finally, a range of radical inhibition operations and radical clock tests were explored to support the reaction process.
Topics & Concepts
ChemistryMetalOrganic chemistryRadical Photochemical ReactionsCatalytic C–H Functionalization MethodsSulfur-Based Synthesis Techniques