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Mogrol suppresses lung cancer cell growth by activating AMPK-dependent autophagic death and inducing p53-dependent cell cycle arrest and apoptosis

He Li, Linling Liu, Hongying Chen, Xin Yan, Ruli Li, Jie Lan, Kunyue Xue, Xue Li, Caili Zhuo, Lan Lin, Lingyu Li, Wu Zhuang, Die Zhang, Xuemei Wang, Wenjing Huang, Yingling Wang, Wei Jiang, Liming Zhou

2022Toxicology and Applied Pharmacology21 citationsDOI

Topics & Concepts

AutophagyAMPKApoptosisCancer researchLung cancerProgrammed cell deathCancer cellCell cycle checkpointCell cycleMedicineCancerBiologyCell biologyInternal medicineKinaseProtein kinase ABiochemistryAutophagy in Disease and TherapyMetabolism, Diabetes, and CancerCell death mechanisms and regulation
Mogrol suppresses lung cancer cell growth by activating AMPK-dependent autophagic death and inducing p53-dependent cell cycle arrest and apoptosis | Litcius