Evorpacept alone and in combination with pembrolizumab or trastuzumab in patients with advanced solid tumours (ASPEN-01): a first-in-human, open-label, multicentre, phase 1 dose-escalation and dose-expansion study
Nehal J Lakhani, Laura Q M Chow, Justin F Gainor, Patricia LoRusso, Keun-Wook Lee, Hyun Cheol Chung, Jeeyun Lee, Yung-Jue Bang, Frank Stephen Hodi, Won Seog Kim, Rafael Santana-Davila, Philip Fanning, Pierre Squifflet, Feng Jin, Tracy C Kuo, Hong I Wan, Jaume Pons, Sophia S Randolph, Wells A Messersmith
Topics & Concepts
PembrolizumabMedicineTrastuzumabInternal medicineOncologyPhases of clinical researchMonoclonal antibodyAntibodyCancer researchPhase (matter)CancerImmunotherapyChemotherapyPD-L1Phagocytosis and Immune RegulationImmunotherapy and Immune ResponsesCancer Immunotherapy and Biomarkers