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Lactate induces tumor-associated macrophage polarization independent of mitochondrial pyruvate carrier-mediated metabolism

Fang Xia, Pei Zhao, Shaoyong Gao, Dongmei Liu, Song Zhang, Mengtian Shan, Yuanyuan Wang, Joerg Herrmann, Qiang Li, Feilong Wang

2023International Journal of Biological Macromolecules62 citationsDOI

Topics & Concepts

Macrophage polarizationIntracellularMetabolismCell biologyMitochondrionChemistryGlycolysisBiochemistryBiologyMacrophageIn vitroImmune cells in cancerEpigenetics and DNA MethylationCancer, Hypoxia, and Metabolism
Lactate induces tumor-associated macrophage polarization independent of mitochondrial pyruvate carrier-mediated metabolism | Litcius