Crude Polysaccharide Produces Silver Nanoparticles with Inherent Antioxidant and Antibacterial Activity
Siva Sankar Sana, Tianyu Hou, Huizhen Li, Ramakrishna Vadde, Nagaraj Basavegowda, Arghya Chakravorty, Divya Vishambhar Kumbhakar, Zhijun Zhang, Narsimha Mamidi
Abstract
Abstract We present an efficient and biologically based process for producing silver nanoparticles (Ag‐NPs) using crude polysaccharides extracted from Perilla frutiscences plants (PFCPS). The PFCPS serves as both a reducing agent and a capping agent during Ag‐NP formation. Characterization of the synthesized Ag‐NPs was performed through various techniques such as Ultraviolet‐Visible (UV‐Vis) absorption spectroscopy, X‐ray diffraction (X‐RD), Fourier transform infrared spectroscopy (FT‐IR), and high‐resolution transmission electron microscopy (HR‐TEM). Antioxidant properties of the Ag‐NPs were evaluated using DPPH, reducing power, and ABTS free radical assays, revealing their potential use as antioxidants. Additionally, Ag‐NPs displayed promising antibacterial activity against Escherichia coli and Klebsiella pneumonia , suggesting their potential for application in medical and healthcare products for the prevention and treatment of infections.