Intratumoural vaccination via checkpoint degradation-coupled antigen presentation
Yu Han, Yicong Ma, Miao Pei, Shenyi Yin, Jiahao Wang, L. Guo, Yike Fang, Weiming Guo, C. L. Deng, Sai Zhao, Xueyin Lu, Jianzhong Jeff Xi, Heng Zhang, Peng R. Chen
Topics & Concepts
ReprogrammingAntigenCancer researchAntigen presentationImmunogenicityImmunologyImmune systemImmunotherapyChimeric antigen receptorTumor microenvironmentChimera (genetics)Cancer immunotherapyBiologyAntigen-presenting cellHumanized mouseVaccinationMedicineImmunogenCytotoxic T cellAntigen processingCancer cellVirologyAntibodyELISPOTT cellCancerImmunotherapy and Immune ResponsesCAR-T cell therapy researchCancer Immunotherapy and Biomarkers