Synthesis and antiproliferative activity of 6BrCaQ-TPP conjugates for targeting the mitochondrial heat shock protein TRAP1
C. Mathieu, Quentin Chamayou, Thi Thanh Hyen Luong, Delphine Naud‐Martin, Florence Mahuteau‐Betzer, Mouâd Alami, Elias Fattal, Samir Messaoudi, Juliette Vergnaud
Topics & Concepts
ChemistryHsp90MitochondrionConjugateMechanism of actionK562 cellsHeat shock proteinCytotoxicityApoptosisBiochemistryCell biologyStereochemistryMolecular biologyIn vitroBiologyGeneMathematical analysisMathematicsHeat shock proteins researchATP Synthase and ATPases ResearchMitochondrial Function and Pathology