Broadly recognized, cross-reactive SARS-CoV-2 CD4 T cell epitopes are highly conserved across human coronaviruses and presented by common HLA alleles
Aniuska Becerra‐Artiles, J. Mauricio Calvo‐Calle, Mary Dawn Co, Padma P. Nanaware, John Cruz, Grant C. Weaver, Liying Lu, Catherine S. Forconi, Robert W. Finberg, Ann M. Moormann, Lawrence J. Stern
Abstract
as a highly conserved CD4 T cell epitope broadly recognized across human populations.
Topics & Concepts
VirologyBiologyEpitopeHuman leukocyte antigenCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)AlleleCoronavirus2019-20 coronavirus outbreakGeneticsAntigenGeneInfectious disease (medical specialty)MedicineDiseaseOutbreakPathologySARS-CoV-2 and COVID-19 ResearchImmunotherapy and Immune Responsesvaccines and immunoinformatics approaches