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Novel quinazolin-2-yl 1,2,3-triazole hybrids as promising multi-target anticancer agents: Design, synthesis, and molecular docking study

Noura F.M. El Hamaky, Abdelrahman Hamdi, Waleed A. Bayoumi, Abdullah A. Elgazar, Magda N.A. Nasr

2024Bioorganic Chemistry42 citationsDOI

Topics & Concepts

ChemistryHeLaDocking (animal)IC50EtoposideMTT assayEGFR inhibitorsErlotinibSorafenibTriazoleStereochemistryApoptosisIn vitroBiochemistryEpidermal growth factor receptorCancer researchReceptorBiologyGeneticsChemotherapyOrganic chemistryNursingHepatocellular carcinomaMedicineCancer therapeutics and mechanismsQuinazolinone synthesis and applicationsCancer Mechanisms and Therapy
Novel quinazolin-2-yl 1,2,3-triazole hybrids as promising multi-target anticancer agents: Design, synthesis, and molecular docking study | Litcius