Tissue-resident CD4 <sup>+</sup> T helper cells assist the development of protective respiratory B and CD8 <sup>+</sup> T cell memory responses
Young Min Son, In Su Cheon, Yue Wu, Chaofan Li, Zheng Wang, Xiaochen Gao, Yao Chen, Yoshimasa Takahashi, Yang-Xin Fu, Alexander L. Dent, Mark H. Kaplan, Justin J. Taylor, Weiguo Cui, Jie Sun
Abstract
Identification of a CD4 + helper T cell population providing in situ help to B and CD8 + T cells in the respiratory mucosa.
Topics & Concepts
Respiratory systemCytotoxic T cellBiologyImmunologyCD8PopulationT cellB cellMolecular biologyMedicineAntigenImmune systemAntibodyIn vitroGeneticsAnatomyEnvironmental healthImmune Cell Function and InteractionT-cell and B-cell ImmunologyImmunotherapy and Immune Responses