Non-small-cell lung cancer: how to manage RET-positive disease
Elisa Andrini, Mirta Mosca, Linda Galvani, Francesca Sperandi, Biagio Ricciuti, Giulio Metro, Giuseppe Lamberti
Abstract
This article reviews the biology, clinicopathological characteristics, targeted therapies and mechanisms of resistance of advanced non-small-cell lung cancer harbouring RET fusions to provide treatment guidance for these patients.
Topics & Concepts
MedicineCabozantinibVandetanibOncologyLung cancerClinical trialErlotinibTargeted therapyDiseaseTyrosine kinaseCancerInternal medicineCancer researchEpidermal growth factor receptorReceptorLung Cancer Treatments and MutationsLung Cancer Diagnosis and TreatmentLung Cancer Research Studies