Optically Manipulated Neutrophils as Native Microcrafts <i>In Vivo</i>
Xiaoshuai Liu, Qing Gao, Shuai Wu, Haifeng Qin, Tiange Zhang, Xianchuang Zheng, Baojun Li
Abstract
, such as active intercellular connection, targeted delivery of nanomedicine, and precise elimination of cell debris, free from the extra construction or modification of the native neutrophils. On the basis of the innate immunologic function of neutrophils and intelligent optical manipulation, the proposed neutrophil microcraft might provide new insight for the construction of native medical microdevices for drug delivery and precise treatment of inflammatory diseases.
Topics & Concepts
In vivoPhagocytosisChemotaxisInnate immune systemComputer scienceCell biologyChemistryBiologyImmunologyImmune systemReceptorBiotechnologyBiochemistryMicro and Nano RoboticsMolecular Communication and NanonetworksNanoplatforms for cancer theranostics