Control of ER-positive breast cancer by ERα expression inhibition, apoptosis induction, cell cycle arrest using semisynthetic isoeugenol derivatives
Mohamed S. Nafie, Nehal H. Elghazawy, Salma M. Owf, Reem K. Arafa, Mohamed A. Abdel-Rahman, Reem K. Arafa
Topics & Concepts
ApoptosisIsoeugenolChemistryCytotoxicityCell cycleCytotoxic T cellIn vivoCell growthCancer cellCell cycle checkpointMCF-7Growth inhibitionDownregulation and upregulationProgrammed cell deathPharmacologyIn vitroBiochemistryCancerBiologyEugenolGeneOrganic chemistryHuman breastBiotechnologyGeneticsBioactive Compounds and Antitumor AgentsCancer therapeutics and mechanismsATP Synthase and ATPases Research